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Research topic

Main interest of our group is the role of mitochondrial (dys) function in the determination of longevity. Our research interest stems from the fact that mitochondrial DNA mutations and dysfunction accumulate with age. We are interested in understanding the molecular mechanisms and signalling pathways that are activated upon mitochondrial dysfunction during aging. We are working on two different model systems: transgenic mice models and the roundworm, Caenorhabditis elegans.

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